Genetic Testing & Counseling

Genetic testing can clarify whether your high triglycerides are driven by inherited factors, information that can shape your care and your family’s.

Helps distinguish MCS from FCS, identifies at-risk family members, and informs therapy choices when standard treatments aren’t working.

A simple blood or saliva sample, analysis of triglyceride-metabolism genes, results in 3 to 6 weeks, shared first with your clinician.

GINA protects against insurance and employer discrimination based on results. Many tests are covered by insurance; financial assistance is often available.

MCS is shaped by many small genetic variants working together, alongside lifestyle and medical factors. While there is no single ‘MCS gene,’ testing can help distinguish MCS from Familial Chylomicronemia Syndrome (FCS), identify family members who may be at risk, and inform decisions about therapy, particularly when standard treatments aren’t working.

• A simple blood or saliva sample collected at a lab or, in some cases, at home
• Analysis of genes involved in triglyceride metabolism (such as LPL, APOC2, APOA5, GPIHBP1, LMF1)
• Results typically returned in 3 to 6 weeks
• A written report, usually shared first with your ordering clinician

Genetic counselors are specially trained healthcare professionals who help you understand what your test results mean, and what they don’t. They can walk through implications for your children, siblings, and parents; discuss insurance and privacy questions; and connect you with research opportunities. A counseling session before testing is just as valuable as one after.

In the United States, the Genetic Information Nondiscrimination Act (GINA) protects against discrimination by health insurers and most employers based on genetic test results. Many tests are covered by insurance when ordered for clinical reasons; financial assistance programs are often available. We can help you find a clinician or counselor familiar with triglyceride disorders.